Louis was born in St. Petersburg, Florida in 1987. As a teenager, he completed the requirements to be an Eagle Scout. he attended Lakewood High School in St. Petersburg, where he played for the Lakewood Spartans high school football team.

In addition to playing quarterback and wide receiver for the Spartans football team, he was also a power forward for the basketball team, and anchored the 4×100 and 4×400-meter relay events for the track team—winning the state championship as a sophomore, with times of 41.59 seconds and 3:24.07 minutes, respectively. Following his senior football season in 2005, he was ranked as one of the top 40 wide receivers in the country.

Louis accepted an athletic scholarship to attend the University of Florida, where he played wide receiver for coach Urban Meyer’s Florida Gators football team from 2005 to 2008. He earned a spot on the 2007 starting roster, and became one of the top receivers on the team. After the end of the regular season, he had 36 catches for 544 yards and five touchdowns.

As a senior team captain in 2008, he led the team in receiving yards (655) and ranked second in receptions (38) and average receiving yards per game (46.8), averaging 17.2 yards per catch; he was also the recipient of the Gators’ Fergie Ferguson Award. He surpassed the 1,000 career-receiving yards mark with 54 yards in the Gators’ victory over South Carolina. Louis extended his streak of consecutive games with a reception to twenty-seven, and scored his final college touchdown on a 20-yard pass in the first quarter of the Gators’ 24–14 BCS National Championship Game victory over the Oklahoma Sooners.

Louis has had an amazing NFL career which has seen him excel with teams like his home team, Tampa Bay Buccaneers and recently the San Francisco 49ers.

Louis graduated from the University of Florida with a bachelor’s degree in 2008.

Murphy was chosen in the fourth round of the 2009 NFL Draft by the Oakland Raiders, and he has played for the Raiders in 2009 through 2011. He made his NFL debut on Monday Night Football against the San Diego Chargers on September 14, 2009, and caught a 56-yard touchdown pass from JaMarcus Russell. In 2009, Murphy caught a touchdown pass that helped the Raiders overcome the Cincinnati Bengals. Later in 2009, Murphy again led his team to a victory over the Pittsburgh Steelers by grabbing an 11-yard touchdown pass from Bruce Gradkowski with nine seconds left in the game.

Louis has had an amazing NFL career which has seen him excel with teams like his home team, Tampa Bay Buccaneers and recently the San Francisco 49ers. Louis caught his first touchdown pass on the season from quarterback Jimmy Garoppolo, who also threw his first touchdown pass as a 49er since being traded from the New England Patriots.